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Mold Update
Wednesday, 30 August 2006

Monday Morning Mold (Mycology) - August 28, 2006

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Monday Morning Mold (Mycology) - August 28, 2006
Mold (Mycology) in the Media
August 28, 2006
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Mold (Mycology) Stories - from Cynthia Anne Coulter (Mulvihill) of Hyde Mulvihill, APC
-- 9th Circuit Ruling clears way for suits over mold in tribal housing (Great Falls Tribune, MT - Aug 27, 2006)
-- Folsom Condo Owners Upset With City, Developer Over Toxic Mold - Residents Of Waterford Place Say Local Government Has Been Slow To Respond (KCRA.com, CA - Aug 24, 2006)
-- Screen for PB Towers mold-prevention generator wins approval (Palm Beach Daily News, FL - Aug 23, 2006)
-- Mold tests might not always be worth the time or money (Danbury News Times, CT - Aug 25, 2006)
-- Band-Aid Repair May Bring Mold Back (KFOXtv.com, TX - Aug 25, 2006)
-- Paradise tackles mold problem at Police Department (Enterprise-Record, CA - Aug 25, 2006)
-- Mold Education: Mycotoxin adducts on human serum albumin: biomarkers of exposure to Stachybotrys chartarum. (Environ Health Perspect. 2006 Aug;114(8):1221-6.)
-- Mold Education: Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain (Environ Health Perspect. 2006 Jul;114(7):1099-107. )
-- Mold & Technology: Radar Technology Detects Hidden Mold (Chief Engineer, IL - Aug 1, 2006)
-- Mold Professionals: Cynthia Coulter Mulvihill (Mold Litigation Consulting)

 

Good Morning,

The news in "big science" this week continues to be astronomy, and I stand corrected. Pluto, Charon and 2003 UB313 are in a new category of "dwarf planets". However, there is a move afoot to rename the category for politically correct reasons. For those of us studying microbiology and mycology, take a look at Mold Education. NOW there is a way to test for human exposure to Stachybotrys chartarum.

This week's photo is one of my favorites -- Dennis Kunkel's photograph of Stachybotrys chartarum, available for purchase in poster size at www.astrogra phics.com.

Hot tips on mold? Please e- mail them to Cynthia A. Coulter Mulvihill at This e-mail address is being protected from spam bots, you need JavaScript enabled to view it


9th Circuit Ruling clears way for suits over mold in tribal housing (Great Falls Tribune, MT - Aug 27, 2006)
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BROWNING — Candice LaMott calls her house "poison." There's black mold under the sink, holes in the walls and a foundation made of chemically treated wood, conditions she believes are responsible for illness in her family and even her mother's death.

When she got this house, she just thought it was a mansion," LaMott said of her mother, from whom LaMott inherited the house. "She didn't care that the wood was going to kill her." LaMott is one of a number of low-income Blackfeet tribal members who sued the tribe's housing authority and the U.S. Department of Housing and Urban Development in 2002 to have their houses, which were built in the late 1970s, replaced.

Click here for 9th Circuit Ruling clears way for suits over mold in tribal housing (Great Falls Tribune, MT - Aug 27, 2006)


Folsom Condo Owners Upset With City, Developer Over Toxic Mold - Residents Of Waterford Place Say Local Government Has Been Slow To Respond (KCRA.com, CA - Aug 24, 2006)
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FOLSOM, Calif. -- Dozens of people in Folsom said they were duped into buying condominiums filled with toxic mold. Now residents are taking their fight to the city, and some are alleging local government officials have been slow to respond.

Condominium owner Mike Sullivan is moving out of the unit he bought for more than $200,000 at the Waterford Place complex in Folsom. He said the condo is filled with mold.

Click here for Folsom Condo Owners Upset With City, Developer Over Toxic Mold - Residents Of Waterford Place Say Local Government Has Been Slow To Respond (KCRA.com, CA - Aug 24, 2006)


Screen for PB Towers mold-prevention generator wins approval (Palm Beach Daily News, FL - Aug 23, 2006)
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[Ed. note: The generator is to keep air conditioning running so mold will not develop, specifically because most condo owners no longer have insurance coverage for it.] The Palm Beach Towers will not be allowed to install a power generator on the grounds of 44 Cocoanut Row as soon as some residents had hoped. But the proposed $1.5 million project gained a bit of turf Wednesday when the town's Architectural Commission voted 4-3 to accept a plan to help screen the equipment from public view.

Commissioners Tom Youchak, William Feldkamp, Leslie Diver and Jeffrey Smith voted for the plan. Nikita Zukov, William Strawbridge and Chairman Morgan "Dix" Wheelock opposed it.

Click here for Screen for PB Towers mold-prevention generator wins approval (Palm Beach Daily News, FL - Aug 23, 2006)


Mold tests might not always be worth the time or money (Danbury News Times, CT - Aug 25, 2006)
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You notice mold splotched across the corner of your living room ceiling. It looks and smells mucky. Time to get an air quality or mold test? Not so fast, warned both the state Departments of Public Health and Consumer Protection Thursday

State officials said molds still need to be removed, but tests are often expensive and unnecessary. Tom St. Louis, an epidemiologist with the Department of Public Health, said an increasing number of people are calling his office with questions on mold testing.

Click here for Mold tests might not always be worth the time or money (Danbury News Times, CT - Aug 25, 2006)


Band-Aid Repair May Bring Mold Back (KFOXtv.com, TX - Aug 25, 2006)
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The cleanup and repair process continues for flood victims. Right now, the biggest concern for the El Paso City-County Health Department is the potential for mold growth. So far, health officials have inspected 140 homes, and say they've come across a lot mold.

It's definitely something every homeowner making repairs needs to look out for. "Took this (floor molding) off, and I found mold and everything. I cleaned it out, sanded the wall there, and then I just put it back, and continued cleaning. That's all I could do," said Alfred Arredondo.

Click here for Band-Aid Repair May Bring Mold Back (KFOXtv.com, TX - Aug 25, 2006)


Paradise tackles mold problem at Police Department (Enterprise-Record, CA - Aug 25, 2006)
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PARADISE -- Crews are working to eradicate an unwelcome visitor to the Paradise Police Department - - mold. Human Resources Manager Denise Farrell updated the council this week on elevated mold levels that were detected on the Police Department building's first floor after a series of water leaks. Although the roof was resurfaced in the past two years, the building's parapet caps and flashing weren't repaired.

Farrell said the problems, including dry rot, buckled siding and mushroom growth, appear to stem from leaking from the parapet cap seals and compromised flashing.

Click here for Paradise tackles mold problem at Police Department (Enterprise-Record, CA - Aug 25, 2006)


Mold Education: Mycotoxin adducts on human serum albumin: biomarkers of exposure to Stachybotrys chartarum. (Environ Health Perspect. 2006 Aug;114(8):1221-6.)
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OBJECTIVE: Despite the growing body of evidence showing adverse health effects from inhalation exposure to the trichothecene-producing mold Stachybotrys chartarum, controversy remains. Currently, there are no reliable assays suitable for clinical diagnosis of exposure. We hypothesized that satratoxin G (SG) -albumin adducts may serve as biomarkers of exposure to this fungus. DESIGN: We studied the formation of adducts of SG with serum albumin in vitro using Western blots and mass spectrometry (MS) and searched for similar adducts formed in vivo using human and animal serum.

RESULTS: Samples of purified human serum albumin that had been incubated with increasing concentrations of SG showed concentration- dependent albumin bands in Western blots developed with anti-SG antibodies. MS analysis found that as many as 10 toxin molecules can be bound in vitro to one albumin molecule. The sequencing of albumin- adduct tryptic peptides and the analysis of pronase/aminopeptidase digests demonstrated that lysyl, cysteinyl, and histidyl residues are involved in the formation of these adducts. Serum samples from three patients with documented exposure to S. chartarum similarly revealed lysine-, cysteine-, and histidine-SG adducts after exhaustive digestion, affinity column enrichment, and MS analysis. These adducts were also found in the sera from rats exposed to the spores of S. chartarum in contrast to control human subjects and control animals. CONCLUSIONS: These data document the occurrence of SG-albumin adducts in both in vitro experiments and in vivo human and animal exposures to S. chartarum. Relevance to clinical practice: SG-amino acid adducts may serve as reliable dosimeter biomarkers for detection of exposure to S. chartarum.

Photo: Stachybotrys spp.

Click here for Mold Education: Mycotoxin adducts on human serum albumin: biomarkers of exposure to Stachybotrys chartarum. (Environ Health Perspect. 2006 Aug;114(8):1221-6.)


Mold Education: Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain (Environ Health Perspect. 2006 Jul;114(7):1099-107. )
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Satratoxin G (SG) is a macrocyclic trichothecene mycotoxin produced by Stachybotrys chartarum, the "black mold" suggested to contribute etiologically to illnesses associated with water-damaged buildings. Using an intranasal instillation model in mice, we found that acute SG exposure specifically induced apoptosis of olfactory sensory neurons (OSNs) in the olfactory epithelium. Dose-response analysis revealed that the no-effect and lowest-effect levels at 24 hr postinstillation (PI) were 5 and 25 microg/kg body weight (bw) SG, respectively, with severity increasing with dose. Apoptosis of OSNs was identified using immunohistochemistry for caspase-3 expression, electron microscopy for ultrastructural cellular morphology, and real-time polymerase chain reaction for elevated expression of the proapoptotic genes Fas, FasL, p75NGFR, p53, Bax, caspase-3, and CAD.

Time-course studies with a single instillation of SG (500 microg/kg bw) indicated that maximum atrophy of the olfactory epithelium occurred at 3 days PI. Exposure to lower doses (100 microg/kg bw) for 5 consecutive days resulted in similar atrophy and apoptosis, suggesting that in the short term, these effects are cumulative. SG also induced an acute, neutrophilic rhinitis as early as 24 hr PI. Elevated mRNA expression for the proinflammatory cytokines tumor necrosis factor-alpha, interleukin-6 (IL-6) , and IL-1 and the chemokine macrophage- inflammatory protein-2 (MIP-2) were detected at 24 hr PI in both the ethmoid turbinates of the nasal airways and the adjacent olfactory bulb of the brain. Marked atrophy of the olfactory nerve and glomerular layers of the olfactory bulb was also detectable by 7 days PI along with mild neutrophilic encephalitis. These findings suggest that neurotoxicity and inflammation within the nose and brain are potential adverse health effects of exposure to satratoxins and Stachybotrys in the indoor air of water-damaged buildings.

Photo: Stachybotrys spp.

Click here for Mold Education: Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain (Environ Health Perspect. 2006 Jul;114(7):1099-107. )


Mold & Technology: Radar Technology Detects Hidden Mold (Chief Engineer, IL - Aug 1, 2006)
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Cutting-edge radar technology may soon make obsolete the slow, destructive and expensive methods now available to detect hidden moisture and mold behind wallboards, according to a report released by the Air-Conditioning and Refrigeration Technology Institute (ARTI).

Existing technology to detect mold behind walls requires stripping wall coverings to inspect hidden surfaces visually or boring holes into numberous wall sections to extract and culture samples. The disassembly and drilling must be done very slowly and carefully to avoid spreading mold spores and fragments through the building, which increases the cost of remediation, according to the report.

Click here for Mold & Technology: Radar Technology Detects Hidden Mold (Chief Engineer, IL - Aug 1, 2006)


Mold Professionals: Cynthia Coulter Mulvihill (Mold Litigation Consulting)
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Cynthia Coulter Mulvihill Cynthia Coulter Mulvihill is a California licensed attorney, admitted to practice in California state and federal courts. She has been the editor and publisher of Monday Morning Mold (Mycology) since 2002.

Ms. Mulvihill provides consulting services to Plaintiffs and Claimants - or potential Plaintiffs and Claimants; Defendants and potential defendants; attorneys; contractors; subcontractors; expert witnesses, remediators, etc. Ms. Mulvihill consults only. Her initial 15-minute consultation is free.

Ms. Mulvihill's confidential services include, depending on who she is retained by, and when:

  • Analysis of property damage and personal injuries
  • Conducting a property inspection
  • Reviewing medical records
  • Determination of the potential for a causal link between mycological issues and personal injuries
  • Research of what needs to be done to prove -- or disprove -- property damage, personal injuries, and their causal links
  • Determination what entity or entities might have caused property damage
  • Reviewing insurance policies to determine if insurance coverage is available for the claims
  • Determination what kind of expert or experts need to be retained to prove or disprove a case
  • Preparation of expert witnesses for depositions
  • Preparation of written discovery
  • Preparation of attorneys for questioning of expert witnesses
Ms. Mulvihill's work is, in general, protected by the attorney-client and attorney work-product privileges.

 

Click here for Mold Professionals: Cynthia Coulter Mulvihill (Mold Litigation Consulting)


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